
Regenerative & Joint Medicine
Arthrosamid ®
Arthrosamid® is a permanent injectable hydrogel that delivers long-lasting, proven pain relief without surgery.

Doctor-Led Arthrosamid® Injections in London & Surrey
Levitas Clinic offers doctor-led Arthrosamid® injections in London (Mayfair), Guildford and Esher for patients with knee osteoarthritis. Arthrosamid® is a non-biodegradable 2.5% polyacrylamide hydrogel (iPAAG) administered as a single intra-articular injection. It integrates into the inner synovial capsule of the knee joint, restoring elasticity, dampening pain signals, and providing sustained relief without open surgery.

Redefining Knee Osteoarthritis Treatment
Arthrosamid® is redefining treatment for knee osteoarthritis, offering a non-surgical option for long-term joint pain relief.
What Arthrosamid® Is
Arthrosamid® is an injectable hydrogel used to treat knee osteoarthritis, administered by a physician experienced in joint injections.
The Procedure
Arthrosamid® is given as a single injection under local anaesthetic, typically carried out as a day case with no overnight stay required.
Comparing Knee Osteoarthritis Treatment Options
How Arthrosamid® compares to hyaluronic acid and steroid injections.
| Treatment Option | Primary Mechanism | Relief Duration | Repeat Frequency |
|---|---|---|---|
| Arthrosamid® Hydrogel | Integrates into the synovial membrane; permanent cushioning & elasticity | Multi-year relief (clinical trial data up to 3–5 years) | Single injection |
| Hyaluronic Acid (HA) | Temporarily lubricates joint fluid | 6 to 12 months | Requires repeat sessions every 6–12 months |
| Steroid Injections | Suppresses acute joint inflammation | 4 to 12 weeks | Used primarily for short-term flare-ups |
Clinical Evidence & Safety
- Mechanism of Action: the 2.5% polyacrylamide hydrogel integrates with the synovial lining over 4 to 12 weeks.
- Clinical Longevity: designed as a single, non-biodegradable injection intended to provide sustained relief - your doctor can discuss expected duration for your individual case at consultation.
- Clinical Accuracy: injections are delivered under local anaesthetic using precision ultrasound guidance.
Private Arthrosamid® Knee Clinics in London & Surrey
Our London clinic is on Woodstock Street, near Bond Street in Mayfair. Arthrosamid® consultations are also available at our Guildford and Esher clinics in Surrey - book a consultation to check your suitability.
Other Treatment Options for Knee Osteoarthritis
Knee osteoarthritis can also be managed through approaches such as weight management, exercise and physiotherapy, walking aids, footwear or insoles, knee braces, oral pain medication, hyaluronic acid injections, and joint replacement surgery in more advanced cases. Your doctor can discuss which options, including Arthrosamid®, may be appropriate for you.
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Frequently Asked Questions
Your Questions, Our Answers
Will I need to stay overnight after treatment?
No - Arthrosamid® is typically given as a single injection under local anaesthetic and is usually carried out as a day case.
How long does Arthrosamid® last?
Arthrosamid® is designed as a single, long-lasting injection rather than a course of treatment. Your doctor can discuss what to expect for your individual case at consultation.
Hear What Our Patients Have to Say

